I have to tell you! We just came back from a wonderful cruise on the Grand Princess. This was our second cruise. Our first was on the Ocean Princess. I was seasick, didn't know I was prone to it so I was caught off guard. I got dramamine from the boutique. Although it did prevent me from being physically sick, I didn't feel well or right the whole week. Therefore, this time, I wanted a better solution. I was hoping to find a non-medicinal solution so this time I tried the seaband. Sorry to say it didn't work at all for me. I was physically sick the second night. I had read many postings from fellow cruisers on sites praising Bonine. This was my backup plan. I purchased some (I'm Canadian - here it is called Bonamine and I purchased it at Zellers right off the shelf). One tablet containing 25mg Meclizine nightly was all I needed. It's good for 24 hours. I had absolutely no side effects whatsoever, I felt completely normal and my old self the rest of the cruise. I was able to enjoy my few drinks a day without any problems. I don't know if a higher dosage would react differently, but 25mg worked beautifully for me. Also, when I returned home I had no physical readjustment time. The first cruise, with the dramamine, took four days to feel myself again. I can't believe I have found the solution for me and I hope it works for you. I look soooooo forward to a future filled with many more cruises problem free. Have a great time and good health!